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ALL THINGS COVID

This is interesting:

WASTEWATER SURVEILLANCE The US CDC has added wastewater surveillance of SARS-CoV-2 RNA to its COVID Data Tracker, as virus levels in sewage water may be capable of providing an early warning signal for transmission surges. The tool comprises data from more than 400 testing sites in 37 states, with more than 34,000 samples representing 53 million US residents collected so far. Hundreds of additional testing sites are expected to begin submitting data to the system in coming weeks. The CDC initiated the National Wastewater Surveillance System (NEWS) in September 2020, and it has become a critical tool for public health officials since it can show where viral loads are changing, which communities are at risk of a surge in cases, and where medical supplies should be deployed.

An additional benefit of the COVID wastewater tracking system is the identification of novel and “cryptic” variants of SARS-CoV-2. Cryptic variants are lineages of SARS-CoV-2 that contain mutations never before observed in humans. A number of cryptic lineages have been detected in the New York City sewer system. The origin of these out-of-the-ordinary lineages, which also have been detected in Missouri and California, has not yet been determined, but the most popular hypothesis is the mutations arose simultaneously in similar animal hosts, such as rodents that live in the sewer systems. Whatever the source, the new surveillance system could be critical in identifying and tracking the next major variant of concern.
Thanks for posting. This is what we need to be doing if we are to move forward with this virus - finding alternative ways to identify and track it, whilst also preventing new variants by adequately ventilating indoor spaces (I don't know if the US is doing this, the UK isn't).
 
Thanks for posting. This is what we need to be doing if we are to move forward with this virus - finding alternative ways to identify and track it, whilst also preventing new variants by adequately ventilating indoor spaces (I don't know if the US is doing this, the UK isn't).
Agreed. The ventilation thing can happen in more prosperous areas where it can be afforded to restructure buildings etc. but I do not see a lot of this happening en mass. Another interesting approach is what my company is doing ~~~ we were scheduled to move into a newly constructed modern office building (by architect Frank Gehry) which is still being completed. Floorplans have the whole open-concept office space, shared spaces and open common areas. We were told than when we do return to the office, the building will only be 67% occuppied at any one time. In other words, we are moving into a hybrid work schedule - part-time at home and partime in the office. We will not have assigned work stations/offices, but will need to book a desk online on the designated day we choose to come in (not unlike buying movie tickets online where you choose your seat) and then plug in our laptops at said station for the day. More details are forthcoming, but that's what it looks like as of now. :shrug:
 
Mask mandates are starting to lift in Cali with the numbers of cases, deaths and positive tests decreasing every week. I think they are still in place for schools in-doors because not all kids are getting the vaccines.

They are being conservative about the lift in LA County, but it's rolling out here as well. I think I will choose to mask when I feel it is necessary, and carry one with me when I go out.

Is it me... or... after Omicron raged, do you feel like you are waiting for the other other shoe to drop?
 
I read a couple of articles this weekend that drove home the horror from covid that some survivors experience. One was a young pregnant woman who was in the hospital 169 days, had a number of strokes. The other was an article about long covid.
Five months post-covid, Nicole Murphy's heart rate is still doing strange things [2.21.22]
Five months after being infected with the coronavirus, Nicole Murphy’s pulse rate is going berserk. Normally in the 70s, which is ideal, it has been jumping to 160, 170 and sometimes 210 beats per minute even when she is at rest — putting her at risk of a heart attack, heart failure or stroke.
No one seems to be able to pinpoint why. She’s only 44, never had heart issues, and when a cardiologist near her hometown of Wellsville, Ohio, ran all of the standard tests, “he literally threw up his hands when he saw the results,” she recalled. Her blood pressure was perfect, there were no signs of clogged arteries, and her heart was expanding and contracting well.
Murphy’s boomeranging heart rate is one of a number of mysterious conditions afflicting Americans weeks or months after coronavirus infections that suggest the potential of a looming cardiac crisis.
Lindsay Polega, 28, an attorney from St. Petersburg, Fla., had never had any medical issues before covid. She had been an all-state swimmer in high school and ran, swam or otherwise exercised an hour or more every day since. But after two bouts with covid, the first in early 2020 and the second in spring 2021, she’s been having what doctors call “hypertensive spikes” that result in shooting pains in her chest that make her shaky and weak. During those incidents, which sometimes occur a few times a day, her blood pressure has gone as high as 210/153 — far above the 120/80, that is considered normal.
For what it's worth, from the comments section:
Physician here. This is what docs have been saying, but not many are listening. Politicians are getting rid of mask mandates, businessmen want to do business, people aren't that interested in boosters, and the prevalent idea is that we're done—just let Covid rip.

But the main problem with Covid for most is not dying of it acutely; it's post-Covid sequelae. These problems, which might affect up to a third of Covid patients (even the percentage affected is not known with much certainty) might give us huge numbers of cardiac patients, chronic lung patients, and patients with early dementia. No one knows how things will shake out. So the human race faces a downside risk from post-Covid illness that is of unknown severity.

I tell some folks I know that the let 'er rip strategy is unwise. But not many listen. Most people have moved on.
People around me are beginning to be more cavalier with mask-wearing. In an office where each knows the others have been vaccinated, two of the three of us weren't wearing a mask. Then, we all decided to put them on.

I've decided to wear a mask until my area has numbers that align with the following article in WaPo:
I'm a 64-year-old vaxxed doctor. Here's how I calculate my covid risk at parties.
Having made it this far without getting covid-19, I think it would be a dumb time for me to catch the virus. Case rates are falling fast enough that the risk will soon be sufficiently low for me to let down my guard. When? There’s no bright line separating safe from unsafe, but case rates of approximately 10 per 100,000 people per day and test positivity rates of less than 1 or 2 percent would make it quite unlikely that a person in line with me in the supermarket or sitting near me at a restaurant has covid. (No state has case rates quite that low, but Maryland is closest, at 11 cases per 100,000; its test-positivity rate is 2.3 percent.) When rates reach that level, I’ll begin eating indoors and will remove my mask in low-risk indoor settings. But I’ll still mask up in very crowded indoor spaces.
The county where I live has 51 cases per 100000, (2 week average). The state has a 2.9% positivity rate. So, I'll wear my mask for a while longer.
 
For what it's worth, from the comments section:

Physician here. This is what docs have been saying, but not many are listening. Politicians are getting rid of mask mandates, businessmen want to do business, people aren't that interested in boosters, and the prevalent idea is that we're done—just let Covid rip.

But the main problem with Covid for most is not dying of it acutely; it's post-Covid sequelae. These problems, which might affect up to a third of Covid patients (even the percentage affected is not known with much certainty) might give us huge numbers of cardiac patients, chronic lung patients, and patients with early dementia. No one knows how things will shake out. So the human race faces a downside risk from post-Covid illness that is of unknown severity.

I tell some folks I know that the let 'er rip strategy is unwise. But not many listen. Most people have moved on.
Today, the UK has dropped all Covid measures. No self-isolation, no masks, nothing at all - letting it rip. They're leaving any decisions (whether to self-isolate or not, mask or not etc...) to people's common sense (which means most people will just carry one with life as 'normal' with Covid. They probably won't even know they've got it as PCR tests are being massively scaled down and LFT's are largely unavailable). The vulnerable just have to hope they avoid it, and who knows how we're going to tell if a new variant appears on the horizon. Free testing is ending soon (easy access to tests has already ended), Covid funding has been stopped, and they are going to stop reporting the figures soon too. Long Covid has never been recognised over here in the last two years, apart from by the medics who are dealing with it. The government have always just said it's post-viral fatigue and nothing to worry about. I hate our government with a passion.
 
Today, the UK has dropped all Covid measures. No self-isolation, no masks, nothing at all - letting it rip. They're leaving any decisions (whether to self-isolate or not, mask or not etc...) to people's common sense (which means most people will just carry one with life as 'normal' with Covid. They probably won't even know they've got it as PCR tests are being massively scaled down and LFT's are largely unavailable). The vulnerable just have to hope they avoid it, and who knows how we're going to tell if a new variant appears on the horizon. Free testing is ending soon (easy access to tests has already ended), Covid funding has been stopped, and they are going to stop reporting the figures soon too. Long Covid has never been recognised over here in the last two years, apart from by the medics who are dealing with it. The government have always just said it's post-viral fatigue and nothing to worry about. I hate our government with a passion.
I hope we keep having access to the numbers here. But, similarly, especially among the vaccinated: how many people are going to take testing seriously? Without that, how reliable are the numbers anyway?
 
I hope we keep having access to the numbers here. But, similarly, especially among the vaccinated: how many people are going to take testing seriously? Without that, how reliable are the numbers anyway?
The numbers are still to be published on weekdays for now, but they've talked about stopping them in April. I can't see people bothering to test if a) they don't need to isolate and b) they have to pay for the tests.
 
Some hope....


Got a Covid Booster? You Probably Won’t Need Another for a Long Time​

A flurry of new studies suggests that several parts of the immune system can mount a sustained, potent response to any coronavirus variant.





  • A colored transmission electron micrograph of a T cell. Antibodies are relatively easy to study, whereas analyzing immune cells requires blood, skill, special equipment and lots of time.

    A colored transmission electron micrograph of a T cell. Antibodies are relatively easy to study, whereas analyzing immune cells requires blood, skill, special equipment and lots of time.Credit...Dr. Klaus Boller/Science Source
Apoorva Mandavilli
By Apoorva Mandavilli
Published Feb. 21, 2022Updated Feb. 24, 2022, 5:12 p.m. ET

As people across the world grapple with the prospect of living with the coronavirus for the foreseeable future, one question looms large: How soon before they need yet another shot?
Not for many months, and perhaps not for years, according to a flurry of new studies.

Three doses of a Covid vaccine — or even just two — are enough to protect most people from serious illness and death for a long time, the studies suggest.
“We’re starting to see now diminishing returns on the number of additional doses,” said John Wherry, director of the Institute for immunology at the University of Pennsylvania. Although people over 65 or at high risk of illness may benefit from a fourth vaccine dose, it may be unnecessary for most people, he added.

Federal health officials have said they are not planning to recommend fourth doses anytime soon.

The Omicron variant can dodge antibodies — immune molecules that prevent the virus from infecting cells produced after two doses of a Covid vaccine. But a third shot of the mRNA vaccines made by Pfizer-BioNTech or by Moderna prompts the body to make a much wider variety of antibodies, which would be difficult for any variant of the virus to evade, according to the most recent study, posted online on Tuesday.



The diverse repertoire of antibodies produced should be able to protect people from new variants, even those that differ significantly from the original version of the virus, the study suggests.
“If people are exposed to another variant like Omicron, they now got some extra ammunition to fight it,” said Dr. Julie McElrath, an infectious disease physician and immunologist at Fred Hutchinson Cancer Research Center in Seattle.

What’s more, other parts of the immune system can remember and destroy the virus over many months if not years, according to at least four studies published in top-tier journals over the past month.
Specialized immune cells called T cells produced after immunization by four brands of Covid vaccine — Pfizer-BioNTech, Moderna, Johnson & Johnson and Novavax — are about 80 percent as powerful against Omicron as other variants, the research found. Given how different Omicron’s mutations are from previous variants, it’s very likely that T cells would mount a similarly robust attack on any future variant as well, researchers said.
This matches what scientists have found for the SARS coronavirus, which killed nearly 800 people in a 2003 epidemic in Asia. In people exposed to that virus, T cells have lasted more than 17 years. Evidence so far indicates that the immune cells for the new coronavirus — sometimes called memory cells — may also decline very slowly, experts said.
 
Some hope....


Got a Covid Booster? You Probably Won’t Need Another for a Long Time​

A flurry of new studies suggests that several parts of the immune system can mount a sustained, potent response to any coronavirus variant.





  • A colored transmission electron micrograph of a T cell. Antibodies are relatively easy to study, whereas analyzing immune cells requires blood, skill, special equipment and lots of time.

    A colored transmission electron micrograph of a T cell. Antibodies are relatively easy to study, whereas analyzing immune cells requires blood, skill, special equipment and lots of time.Credit...Dr. Klaus Boller/Science Source
Apoorva Mandavilli
By Apoorva Mandavilli
Published Feb. 21, 2022Updated Feb. 24, 2022, 5:12 p.m. ET

As people across the world grapple with the prospect of living with the coronavirus for the foreseeable future, one question looms large: How soon before they need yet another shot?
Not for many months, and perhaps not for years, according to a flurry of new studies.

Three doses of a Covid vaccine — or even just two — are enough to protect most people from serious illness and death for a long time, the studies suggest.
“We’re starting to see now diminishing returns on the number of additional doses,” said John Wherry, director of the Institute for immunology at the University of Pennsylvania. Although people over 65 or at high risk of illness may benefit from a fourth vaccine dose, it may be unnecessary for most people, he added.

Federal health officials have said they are not planning to recommend fourth doses anytime soon.

The Omicron variant can dodge antibodies — immune molecules that prevent the virus from infecting cells produced after two doses of a Covid vaccine. But a third shot of the mRNA vaccines made by Pfizer-BioNTech or by Moderna prompts the body to make a much wider variety of antibodies, which would be difficult for any variant of the virus to evade, according to the most recent study, posted online on Tuesday.



The diverse repertoire of antibodies produced should be able to protect people from new variants, even those that differ significantly from the original version of the virus, the study suggests.
“If people are exposed to another variant like Omicron, they now got some extra ammunition to fight it,” said Dr. Julie McElrath, an infectious disease physician and immunologist at Fred Hutchinson Cancer Research Center in Seattle.

What’s more, other parts of the immune system can remember and destroy the virus over many months if not years, according to at least four studies published in top-tier journals over the past month.
Specialized immune cells called T cells produced after immunization by four brands of Covid vaccine — Pfizer-BioNTech, Moderna, Johnson & Johnson and Novavax — are about 80 percent as powerful against Omicron as other variants, the research found. Given how different Omicron’s mutations are from previous variants, it’s very likely that T cells would mount a similarly robust attack on any future variant as well, researchers said.
This matches what scientists have found for the SARS coronavirus, which killed nearly 800 people in a 2003 epidemic in Asia. In people exposed to that virus, T cells have lasted more than 17 years. Evidence so far indicates that the immune cells for the new coronavirus — sometimes called memory cells — may also decline very slowly, experts said.
Interesting, thanks for posting. It seems to go against what they're saying here, that booster immunity starts waning after 10 weeks. We're starting fourth doses for the elderly and vulnerable (age over 12) soon.
 
Interesting, thanks for posting. It seems to go against what they're saying here, that booster immunity starts waning after 10 weeks. We're starting fourth doses for the elderly and vulnerable (age over 12) soon.
The article said that for over age 65 and those who are immune compromised should probably still get a 4th shot - but for everyone else, the 3rd booster could last a while. Also today, Los Angeles County is lifting the indoor mask mandate, except for medical offices et al. I will probably carry one at all times and wear it in very crowded stores or indoor places.
 
The article said that for over age 65 and those who are immune compromised should probably still get a 4th shot - but for everyone else, the 3rd booster could last a while. Also today, Los Angeles County is lifting the indoor mask mandate, except for medical offices et al. I will probably carry one at all times and wear it in very crowded stores or indoor places.
I've always felt masks haven't been as politicised over here as they have been in the US. When our mask mandates were dropped, many carried on wearing them regardless. However, since Thurs when all restrictions were dropped, there seems to be very, very few people wearing them now. I've suddenly become very conscious of wearing mine, though I am still wearing it.
 
It's weird, they technically lifted the mask mandate but every store and market I have been - we are all still wearing our masks. Maybe after two years it just feels weird not to have one on. :shrug:
 
Unsurprisingly, now they've let rip, I've got Covid.

Self-isolating, but weird to think that I could go about my daily business knowingly spreading it (not that I've the energy to leave the sofa).
oh, no :( Take care, Maple!

Did anyone see Ron DeSantan (FL Gov) telling teens at a school he was visiting to take off their masks and stop spreading covid fear <-- what a total asshat!
 
oh, no :( Take care, Maple!

Did anyone see Ron DeSantan (FL Gov) telling teens at a school he was visiting to take off their masks and stop spreading covid fear <-- what a total asshat!
Yes, and most of them did. One didn't and I couldn't tell if there were 2, one of them was hidden behind DeSantis in the video. Now he's fundraising off of it to all the (maskless) mouthbreathers.

Politico - ...In a Thursday campaign email attempting to spur donations “before the truth is silenced,” DeSantis blasted the “corrupt and biased legacy media” for chastising him over his claims that “masks are political theater.” The DeSantis campaign also created a hype video over his controversial brief scolding of high school students that slams Democrats like California Gov. Gavin Newsom and Stacy Abrams for going maskless at public events...
 
Yes, and most of them did. One didn't and I couldn't tell if there were 2, one of them was hidden behind DeSantis in the video. Now he's fundraising off of it to all the (maskless) mouthbreathers.

Politico - ...In a Thursday campaign email attempting to spur donations “before the truth is silenced,” DeSantis blasted the “corrupt and biased legacy media” for chastising him over his claims that “masks are political theater.” The DeSantis campaign also created a hype video over his controversial brief scolding of high school students that slams Democrats like California Gov. Gavin Newsom and Stacy Abrams for going maskless at public events...
DeSatan is such a creep. :disbelief:
 
My question now is with all the disinfecting we've done, what about all the super bugs that have been a major problem before this . How did this impact those?
 
America's Biggest Popdick - of course, that would be Rand Paul - introduced a bill yesterday to eliminate Dr. Fauci's position within the government.

How in the world do you become as stupid as Rand Paul? Do you take pills, or shots, or knocks to the head? That dude is just an idiot, a cretin, a moron. What kind of fool supports him?
 

The new hot spot​

Even as Covid-19 cases and deaths have continued to decline in the United States, there are some worrisome developments around the world. Today, I’ll walk through them — and explain their implications for the U.S.​

The Pacific region …​

After more than two years of mostly fighting off Covid, Hong Kong has become the world’s worst hot spot. The main problem, as in so many other places, is vaccine skepticism.​
Heading into the current outbreak, nearly 40 percent of Hong Kong’s population was not vaccinated, and more than half of people over 70 — the age group most vulnerable to severe Covid — were unvaccinated.​
Why? Many Hong Kong residents do not trust the government, given the increasing repression by China. Others are dubious of Western medicine or have been influenced by misinformation, as my colleagues Alexandra Stevenson and Austin Ramzy have reported. “I worry that the side effects of vaccination will kill me,” Lam Suk-haa, who’s 80 years old, told The Times last month. “I won’t get vaccinated as long as I have a choice.”​
Until recently, Hong Kong — like mainland China — had been largely successful in keeping out the virus, which meant that vaccine skepticism did not bring large costs. But the Omicron variant is so contagious that it overwhelmed Hong Kong’s “zero-Covid” strategy.​
Adding to the problem, many residents have received Sinovac, a Chinese-made vaccine that is less effective than the vaccines designed in the U.S. and Europe — by Moderna, Pfizer, Johnson & Johnson and AstraZeneca. Although the Pfizer vaccine is available in Hong Kong, many residents wrongly fear that it has dangerous side effects. Sinovac still provides meaningful protection against severe illness, but not as much as the Western vaccines.​
The death rate in Hong Kong has soared this month, surpassing 25 per 100,000 residents in the past week. That’s not as high as New York’s peak death rate in the spring of 2020, but it is higher than in any country today. And Hong Kong’s rate will probably continue rising, because new case numbers did not start falling until about a week ago; death trends typically lag case trends by about three weeks.​
 
America's Biggest Popdick - of course, that would be Rand Paul - introduced a bill yesterday to eliminate Dr. Fauci's position within the government.

How in the world do you become as stupid as Rand Paul? Do you take pills, or shots, or knocks to the head? That dude is just an idiot, a cretin, a moron. What kind of fool supports him?

Kentucky keeps electing him. :shrug:
 

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